Painting blood vessels and atherosclerotic plaques with an adhesive drug depot
نویسندگان
چکیده
منابع مشابه
Painting blood vessels and atherosclerotic plaques with an adhesive drug depot.
The treatment of diseased vasculature remains challenging, in part because of the difficulty in implanting drug-eluting devices without subjecting vessels to damaging mechanical forces. Implanting materials using adhesive forces could overcome this challenge, but materials have previously not been shown to durably adhere to intact endothelium under blood flow. Marine mussels secrete strong unde...
متن کاملDES: atherosclerotic plaques and drug sorption
Atherosclerosis is the most common cardiovascular disease that is characterized by the narrowing and hardening of arteries. This process is caused by cholesterol deposition due to inflammation of the intima. Drug eluting stents(DES)metallic structures coated by a polymer containing an anti-proliferative agent which is gradually released are the most common drug delivery systems used in the trea...
متن کاملPrevalence of Atherosclerotic Plaques in Autopsy Cases with Noncardiac Death
Background and Objective: Ischemic heart disease (IHD) following atherosclerosis is the most common cause of cardiac deaths world wide. We aimed to investigate the pathologic features of atherosclerosis in non cardiac death cases to have an estimate of atherosclerosis prevalence in Mashad (North east of Iran). Patients and Methods : This descriptive (cross sectional) study was done, during ...
متن کاملBlood flow and the localization of atherosclerotic plaques.
Saphenous veins used in aortocoronary bypass procedures slowly narrow. The narrowing and atherosclerosis appear to develop in reaction to the new flow conditions present in the saphenous veins. Localization of atherosclerosis in the arterial system also suggests that local flow conditions play a role in atherogenesis; plaques are characteristically found in regions of separated flow. The patter...
متن کاملOriginal Contributions Blood Flow and the Localization of Atherosclerotic Plaques
Saphenous veins used in aortocoronary bypass procedures slowly narrow. The narrowing and atherosclerosis appear to develop in reaction to the new flow conditions present in the saphenous veins. Localization of atherosclerosis in the arterial system also suggests that local flow conditions play a role in atherogenesis; plaques are characterically found in regions of separated flow. The pattern o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2012
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.1217972110